Post Doc Position in Cancer Biology

Post Doc Position in Cancer Biology

IIT - Istituto Italiano di Tecnologia

Milan, Italy

The selected candidate will join the characterization of a number of novel YAP/TAZ regulators that we recently identified by a loss of function genetic screen (unpublished), with the aim of addressing their relevance in cancer stem cells regulation, chemo-resistance and metastasis in Breast Cancer models. The ideal candidate should have a strong interest in at least one of the following topics (i) understanding upstream regulatory mechanisms; (ii) the dissection of transcriptional and epigenetic networks (RNA-seq, ChIP-seq, single-cells RNA-seq), both in-vitro and in-vivo and (iii) use of CRISPR/CAS9 based genome editing for in-vitro and in-vivo studies (iv) mechanistic investigation of transcription induced replicative stress. The ideal candidate should be highly skilled in basic molecular biology techniques, cell culture and basic biochemistry. Previous experience in working with animal models, organoids, in Next Generation Sequencing techniques or bioinformatics will be a plus.

Within the team, your main responsibilities will be

  • Work independently as well as participate in an interactive, team-oriented project management;
  • Be proactive in hypothesis building and feasibility assessments;
  • Troubleshoot and Implement solutions.

ESSENTIAL REQUIREMENTS

  • A PhD in life Science, Biophysics or Computational Biology and similar disciplines;
  • Documented experience in at least one of the following areas: Molecular Biology, Cell Biology, Protein Biochemistry, Breast Cancer Models or Genomics;
  • A strong publication record;
  • The ability to properly report, organize and publish research data;
  • Documented experience in coaching junior scientists;
  • Good command in spoken and written English.

ADDITIONAL SKILLS

  • Experience on Signal transduction analysis, Transcriptional and epigenetic mechanisms, DNA damage response and replicative stress;
  • Knowledge of R, C/C++, phyton programming languages;
  • Good communication skills;
  • Strong problem solving attitude;
  • High motivation to learn;
  • Spirit of innovation and creativity;
  • Good in time and priority management;
  • Ability to work in a challenging and international environment;
  • Ability to work independently and collaboratively in a highly interdisciplinary environment.

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© EuroJobsites 2021

EuroJobsites is a registered company number: 4694396 VAT number: GB 880 9055 04

Registered address: EuroJobsites Ltd, Unit 8, Kingsmill Business Park, Kingston Upon Thames, London, KT1 3GZ, United Kingdom

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