The planned research project for the announced position is devoted to revealing molecular mechanisms in interactions between small mineral (metal oxide) nanoparticles and proteins. The results from this is expected to provide principal theoretical insights in development of new nanotechnology approaches in biomedicine and agriculture. Complexation between nanoparticles and proteins will be visualized by various techniques such as electron microscopy, atomic force microscopy as well as by X-ray single crystal studies of complexes of inorganic and organic molecules in the solid state and by nuclear magnetic resonance spectroscopy in solution. The studies will in addition to structural characterization of the interacting between nanoparticles and protein molecules, also involve heterological expression of the target proteins as well as biochemical characterization and purification of those.
The recruited postdoc will be working in a challenging, but highly rewarding, research project with the aim to reach a deeper molecular and structural understanding of the interaction between small mineral nanoparticles and proteins. The enrolled person is expected to be highly self-driven, but will be working in close contact and in collaboration with other team members of the inorganic chemistry group and the structure biology group at the department.
The candidates for the position should hold a doctoral degree in Chemistry, Materials Science, Structure Biology, Biochemistry, Biotechnology, Molecular Biology or related subjects. The applicant should have a strong interest for and general expertise in molecular or supramolecular crystallography and in protein separation and purification. Experience in techniques applying and characterizing nanomaterials, especially transmission electron microscopy are of merit.
Research experience after receiving a doctoral degree (ca. 1-3 years) is preferred. The applicant shall have well-documented competence in structural studies of biological macromolecules either by X-ray crystallography or Cryo-EM. Experience with molecular biological methods and biophysical characterization of proteins is desired. Strong communication skills in oral and written English is a requirement.
Personal metaskills, in addition to technical proficiency and competence, including strong skills in collaboration, organization, responsibility and supervision of students and colleagues are of great importance. We are looking for a highly motivated candidate who is interested in pursuing academic research in the forefront of this research area, and we place great emphasis on the personal qualities of a suitable candidate for the position.
The position is intended for a junior researcher and we are primarily looking for people who have completed their doctorate no more than three years ago.