Technician - National Facility for Genome Engineering

HT - Human Technopole

Technician - National Facility for Genome Engineering

HT - Human Technopole

Milan, Italy

Job description


The Human Technopole (HT) is a new interdisciplinary research institute in Milan, Italy, created and supported by the Italian government whose aim is to develop innovative strategies to promote human health through a multidisciplinary and integrated approach, combining genomics, computational and structural biology, neuroscience, and data and decisions sciences. HT has the mission of conducting cutting-edge research but also to translate innovation into methods and tools available to the entire National scientific community. To this end, HT is opening National Facilities that will provide state-of-the-art research infrastructure for Structural Biology, Light Imaging, Genomics, Genome Engineering, and Data Handling and Analysis.

Overview - National Facility for Genome Engineering and Disease Modelling

The core mission of the National Facility for Genome Engineering and Disease Modelling is to enable patient-specific disease modelling at scale by translating, benchmarking and standardising laboratory protocols into automated workflows, integrating state-of-the-art robotic and bioengineering platforms through a highly multidisciplinary approach. Operating in close collaboration with the Genomics and Advanced Imaging National Facilities, as well as the Flow Cytometry and Electrophysiology support units, GEDI develops transformative technologies to achieve the Human Technopole vision of high-definition biomedicine. This involves utilizing increasingly sophisticated organoid systems at single-cell multiomic resolution, with a strong emphasis densely phenotyped clinical cohorts.

The successful candidate will report to the Head of the Facility and will have the opportunity to work in a multidisciplinary environment to develop and support the execution of experimental activities in the following areas: Reprogramming of somatic cells into induced pluripotent stem cells (iPSCs), followed by characterization and banking of the generated iPSCs.

Job requirements

Mandatory requirements:

  • A master’s degree in molecular biology, genetics, biochemistry, or in a related field of the life sciences is required;
  • At least 1 year of relevant work experience;
  • Experience with cell culture techniques and maintenance of immortalized/tumor cell lines;
  • Experience in basics molecular biology (DNA and RNA manipulation, cloning, RT-CR);
  • Experience and skills in performing repetitive and specialized laboratory experimental procedures;
  • Fluency in English – HT is an international research institute.

Preferred requirements:

  • Experience with human pluripotent stem cell lines (reprogramming from somatic cells, maintenance and differentiation protocols);
  • Experience in molecular biology (sequencing, single cell manipulation, Flow Cytometry);
  • Familiarity with Protein Biochemistry methods (immunoblotting and immunoprecipitation techniques).

Organizational and social skills:

  • Ability to manage competing priorities in a fast-paced environment and to work independently;
  • Strong interpersonal skills demonstrated by the ability to lead and gain the assistance and cooperation of others in a team endeavor;
  • Ability to build trust through operating with transparency and creating an open and positive environment;
  • Ability to work in a multi-cultural, multi-ethnic environment with sensitivity and respect for diversity.

Application Instructions

Please apply online sending:

  • A full CV;
  • A motivation letter;
  • Referee contacts.


  • HT seeks for scientific excellence, we recruit the best scientific talents through international, open calls and meritocratic selection procedures;
  • Our working environment is international, friendly and inclusive. Our scientists work together across disciplines on research topics of biomedical relevance, leveraging synergies between their diverse skillsets and methodological approaches;
  • We believe that highly diverse teams yield the best and most innovative results;
  • We engage in outward-facing scientific activities aimed at benefiting the national and international research community. Training is also at the heart of our activity, with initiatives and opportunities for our staff, including scientific courses, conferences and workshops.

Main benefits

  • Welfare plans;
  • Canteen service;
  • Work-life balance provisions;
  • Italian language training for foreigners;
  • Maternity leave up to 1 year and other support for new parents;
  • Possibility of flexible working hours;
  • Support for relocation.

Special consideration will be given to candidates who are part of the protected categories list, according to L. 68/99.

Number of positions offered: 1
Contract offered: CCNL Chimico Farmaceutico, 3 years Fixed-term - Employee level
Salary range: up to 45k (RAL) depending on the seniority. Tax benefits where applicable.
The position is based in

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