Are you looking for a challenging postdoc position and do you have an interest in performing innovative basic/early translational research with a focus on mapping and targeting fibroblast subsets in inflammatory bowel disease (IBD) and pancreatic cancers? Then we might have the perfect position for you!
As a postdoc you will work in the Research Laboratory of the Gastroenterology and Hepatology department of the LUMC. The IBD project will be performed in close collaboration with the Translational Research Center for Gastrointestinal Disorders in Leuven.
Our laboratory and the associated Stroma Research Center Leiden is focused on the role fibroblasts in intestinal inflammation and gastrointestinal cancers. We use state-of-the-art (imaging) technologies in combination with advanced preclinical and near-patient models. You will be working on a research project supervised by Dr. Marieke Barnhoorn and Dr. Luuk Hawinkels.
This project will focus on the role of fibroblasts in both IBD and gastrointestinal cancers. One part of the project is focused on performing imaging mass cytometry to identify different fibroblast subsets in (complications of) IBD. This is accompanied by mechanistic studies in 3D-in vitro models to investigate the interaction between fibroblasts, epithelial and immune cells. Finally, we will also evaluate strategies to target or modify fibroblast subsets in IBD and pancreatic cancer.