The research focuses on the realization of an instrument for the spectral and spatial characterization of the “fundus” of the human eye. The new instrument will be part of a multi-observable measurement platform aimed to work as a biosensor for a plethora of neurodegenerative diseases such as Alzheimer’s disease (AD). In particular, it is known that tau protein aggregates in the AD early stage, producing Rayleigh scattering and thus enhancing reflectance at high frequency (small wavelengths). The instrument will be preliminarily tested with the spectral characterization of phantom or model eyes and then optimized for the in-vivo operation on human patients. By synchronizing the sensor, actuators and illumination, we plan to characterize spatially and spectrally all the areas of the retina.
This open position is financed by IIT within the IIT-CrestOptics JointLab project.