(Senior/Principal) Scientist - Biopharmaceutical Drug Product Design & Modeling

(Senior/Principal) Scientist - Biopharmaceutical Drug Product Design & Modeling

RCPE - Research Center Pharmaceutical Engineering

Graz, Austria

Duties and responsibilities

  • Develop and apply mechanistic and effective methodologies for advanced biopharmaceutical product profiling, including:
    • Mechanistic understanding of pre-formulation/formulation and biopharmaceutics characteristics critically impacting drug release and absorption;
    • Development/optimization of innovative in vitro & in silico methodologies for improved IVIVC;
    • Develop and maintain a contemporary in-depth understanding of the innovative science and technology used to characterize the biopharmaceutical performance of oral and inhalation dosage forms;
    • Implementation of risk assessment approaches to support decision making processes during drug development.
  • Develop new scientific ideas, methods and technologies in the field of biopharmaceutics and establish small biopharmaceutics team;
  • Execute experimental/simulation work and provide trainings for personnel on biopharmaceutical product profiling tools;
  • Support scientific output and supervise scientific project work, including supervision of PhD students and diploma/master thesis;
  • Actively participate in project teams/meetings/scientific networks;
  • Produce project reports and publish research results in reputed journals.

Requirements

  • A technical or natural scientific MS degree/A PhD and 2-5 years research experience in a field related to the tasks of the project;
  • Knowledge of biorelevant dissolution testing, method development as well as in physiologically-based PK (PBPK) modeling with hands-on experience with PBPK software such as GastroPlus;
  • Knowledge on oral biopharmaceutics as well as in inhalation biopharmaceutics as an advantage;
  • Professional conduct and communication skills in dealing with international clients, partners and colleagues;
  • Interest and experience in performing top-level and target-oriented research at the interface of basic science and industrial application.

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