Postdoc Position in Molecular Genetics

Postdoc Position in Molecular Genetics

VIB

Leuven, Belgium

Job description

Are you interested in unraveling a central, yet understudied mechanism in eukaryotic cells? Join our multidisciplinary and international team to perform ground-breaking research aimed at understanding how cells control gene activity and protein expression.

We are looking for a highly motivated and talented postdoctoral scientist with a PhD in biological engineering, molecular biology, genetics and/or microbiology (or equivalent). You will join a young and motivated international team of scientists working on regulatory genomics, within the framework of the European Research Council (ERC)-funded Synergy Grant EPIC. This exciting project aims to understand how cells control gene activity and protein expression, which is crucial to understanding how cells function.

You will study transcriptional and post-transcriptional regulation leveraging the unparalleled molecular toolbox of the eukaryotic model system Saccharomyces cerevisiae and other eukaryotic fungal species. You will perform innovative assays to probe the cells across all layers of gene regulation (i.e. chromatin, DNA, RNA and protein level) under different environmental conditions.

Your work will consist of a variable mix of experiments and analyses, including basic microbiology, transformation, high-throughput phenotyping using robots, state-of-the-art DNA and RNA sequencing and analysis, synthetic biology approaches. You will be based in Leuven, but will also collaborate with the two other groups involved in this project with complementary expertise (Vicente Pelechano, Karolinska Institute, development of high-throughput omics assays and Julien Gagneur, Technical University of Munich, AI and bioinformatics) via regular online meetings and short research stays. In this way, your data will contribute to building a model of the regulatory code. You will perform experimental validation by using this model to design genes and cells for biotechnological applications.

Profile

Essential

  • You have a PhD degree in biotechnology, biology, biochemistry, bio-engineering or a related field;
  • You are familiar with data analysis using R;
  • You are fluent in English, for both written and oral communication;
  • You are an enthused team player who is open and respectful to other cultures, opinions and ways of life;
  • You are accurate and critical of your work and its implementation;
  • You are willing to participate in the general lab organization;
  • You have a strong ability to multi-task and meet timelines.

Desirable but not required

  • Experience with yeast molecular biology (PCR, transformation, large-scale assays) is considered a strong plus.

Key personal characteristics

  • You love working in a multicultural, international and multidisciplinary team and enjoy diversity.

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