We are seeking to appoint a highly motivated and experienced scientist with considerable expertise in mass spectrometry to lead major research collaborative projects with our group leaders. The successful applicant will independently work together with our group leaders and staff within their laboratory to design and undertake collaborative mass spectrometry studies. The successful applicant will analyse and interpret proteomics data for publication and grant applications. The post holder will also be involved in the long term development of mass spectrometry systems in the MRC PPU and liaising effectively with the other research staff who work within the MRC PPU mass spectrometry facility. This position provides an exciting opportunity to be involved in world-class research projects and for the successful applicant to carve themselves a major international reputation.
Applicants should have significant experience of proteomics in an academic or industry environment. They should have a significant publication track record and knowledge of the operation mass spectrometers, particularly instruments available within the MRC PPU including Orbitrap Lumos, Exploris, Exactive HF-X or Bruker timsTOF. An excellent knowledge of quantitative proteomics workflows, sample preparation and data analysis of global proteomics and good understanding of statistical knowledge is essential. Previous work with phosphorylation or ubiquitylation post-translational modifications would be advantageous. A good knowledge in Python, R and/or MATLab and ability to write and develop scripts as well as modify and implement open source or published code is also desirable. The ability to work independently and communicate effectively with staff at all levels is also essential.