In this role you will design, execute, and analyze pooled CRISPR knockout, activation, and interference screens to uncover novel therapeutic targets and contribute to the group's translational programs; Establish, optimize, and routinely perform cell-line
Design and execute genome-wide CRISPR knockout, CRISPRa, and CRISPRi screens in mammalian cell models. Validate screening hits using arrayed CRISPR experiments and orthogonal functional assays in relevant disease models Establish, optimize, and routinely
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