In this role you will design, execute, and analyze pooled CRISPR knockout, activation, and interference screens to uncover novel therapeutic targets and contribute to the group's translational programs; Establish, optimize, and routinely perform cell-line
Design and execute genome-wide CRISPR knockout, CRISPRa, and CRISPRi screens in mammalian cell models. Validate screening hits using arrayed CRISPR experiments and orthogonal functional assays in relevant disease models Establish, optimize, and routinely
The PostDoc research will be part of a multi-center research project on applying and combining multi-modal 2D and 3D imaging methods for understanding metastasis and tumor deposit formation in colorectal tumors. Specifically, the work will focus on
The European Molecular Biology Laboratory (EMBL) is one of the highest ranked scientific research organizations in the world. The Headquarters Laboratory is located in Heidelberg (Germany) and the outstations are in Grenoble (France), Hamburg (Germany), Hinxton (UK) and Monterotondo (Italy).
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