This project aims to further understand the reprogramming of cells exposed to early and chronic hypoxia in multiple experimental models, with a particular focus on CRISPR and single cell sequencing. The project will involve perturbation experiments in
Design and perform genetic and genomics screens to reconstruct maps of functional interactions across the ERN; Design and carry out functional experiments to mechanistically dissect the basis of identified interactions; Identify physiologically relevant
Develop a comprehensive and cutting-edge experimental approach to interrogate the ERN; Design and perform advanced genetic and genomics screens to reconstruct maps of functional interactions across the ERN; Design and carry out functional experiments to
The European Molecular Biology Laboratory (EMBL) is one of the highest ranked scientific research organizations in the world. The Headquarters Laboratory is located in Heidelberg (Germany) and the outstations are in Grenoble (France), Hamburg (Germany), Hinxton (UK) and Monterotondo (Italy).
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