Postdoctoral Research Associate in Biology

Postdoctoral Research Associate in Biology

University of York

York, United Kingdom

GBP 37,694 - 42,254 per year

We are seeking to appoint a highly motivated postdoctoral researcher to join the team working in the molecular chaperone and neurodegeneration lab headed by Dr Han-Jou Chen. The research scope of the team is to investigate the molecular and cellular pathogenesis underlying neurodegenerative diseases with the aim to develop new therapeutic strategies for neurodegeneration.

Role

Our research investigates the molecular and cellular pathogenesis underlying neurodegeneration with the eventual goal of developing new therapeutic strategies to combat neurodegenerative diseases affecting millions of people globally. Our previous work identified a dysregulation of the JNK signaling pathway that contributes to aberrant cell response and toxicity, mediated by disease-associated TDP-43 protein expression. To carry this forward, the successful candidate will further characterise the molecular interaction between TDP-43 and JNK signaling, and dissect the involvement of JNK signaling during TDP-43-mediated neurodegeneration.

Skills, Experience & Qualification needed

• The successful candidate will be an experienced researcher with a PhD or equivalent research experience in the relevant area of Neuroscience or Cell/Molecular Biology.
• Ability to carry out independent and collaborative research.
• Experience in molecular and cell biology research from designing, running experiments, to data analysis and reporting, both in writing and presentation.
• Experience of working with iPSCs and Drosophila is desirable but not essential.
• A strong commitment to the work and ability to be comfortable in teamwork.
• Ability to be supportive and to work proactively with colleagues and students.