Postdoctoral Researcher in Single-molecule Biophysics

Postdoctoral Researcher in Single-molecule Biophysics

Uppsala University - Department of Cell and Molecular Biology

Uppsala, Sweden

Duties

The postdoctoral researcher will investigate fundamental mechanisms underlying programmable DNA recognition and genome reorganization. This project offers a unique opportunity to develop innovative experimental approaches aimed at resolving key questions in molecular specificity, DNA remodeling, and cellular genome dynamics. The successful candidate will combine advanced single-molecule fluorescence microscopy with a diverse toolkit of molecular biology and in vitro biochemical approaches to advance our understanding of this emerging area.

Requirements

We are seeking a highly motivated candidate with a PhD in biophysics, biochemistry, physics, molecular biology, cell biology, or a related field. The degree must be obtained by the time the employment decision is made. In accordance with eligibility requirements, priority will be given to candidates who obtained their PhD no more than three years before the application deadline. The three-year period is calculated from the application deadline and may be extended in cases of documented special circumstances, including sick leave, parental leave, or duties in labour unions.

The candidate should be able to work independently and must have excellent proficiency in English, as the position is based in an international research environment. We value strong collaborative skills, self-motivation, and a genuine interest in basic research, particularly in addressing fundamental biological questions through quantitative approaches.

Additional qualifications

Prior experience and a strong interest in fluorescence microscopy, single-molecule microscopy, and related quantitative approaches are highly valued. Experience with protein-DNA or nucleic acid-protein complexes, DNA recognition systems, genome engineering approaches, or in vitro biochemical reconstitution will be considered an advantage.