PostDoc in Computational Biology: Study of the Crosstalk Between the Tumor and Immune System in Metastatic Colorectal Cancer

PostDoc in Computational Biology: Study of the Crosstalk Between the Tumor and Immune System in Metastatic Colorectal Cancer

Empa - Swiss Federal Laboratories for Materials Science and Technology

St. Gallen, Switzerland

Your tasks

We are looking for a highly motivated candidate with genuine interest in biomedicine and a strong proficiency in data analysis. In this project, we study how tumor-intrinsic genetic alterations and spatially organized microenvironmental niches jointly shape metastatic progression and therapy response in colorectal cancer. The project is strongly oriented towards clinical applications and identification of new therapeutic avenues.

The key responsibilities include:

• Working closely with interdisciplinary project partners;
• Integrating newly generated datasets with multi-omics profiles of tumors from previous studies;
• Developing new machine learning models through collaboration with the Swiss Data Science Centre;
• Establishing data analysis pipelines, writing manuscripts and presenting at scientific conferences.

Your profile

Required qualifications include a PhD degree in computational biology or a related field. We are looking for a research-driven and results-oriented team player.

Ideal profile includes following competencies and experience:

• Strong programming skills, deep statistical knowledge and a proven track record with machine learning;
• Solid knowledge of tumor biology, signaling pathways and the tumor microenvironment;
• Strong publication record;
• Fluency in English and excellent communication and writing skills;
• Experience in the analysis of single-cell and spatial transcriptomics datasets is desirable.