Postdoctoral Researcher - Time-Resolved Structural Biology (XFEL/Synchrotron)

Postdoctoral Researcher - Time-Resolved Structural Biology (XFEL/Synchrotron)

Jagiellonian University, Nogly Lab

Kraków, Poland

PLN 130,700 per year gross

The Project & Key Tasks

We are seeking an ambitious Postdoc to lead a high-impact project on the structural dynamics of cyanobacterial halorhodopsins. This project has a "running start": diffracting crystals (2.3 Å) and purification protocols are already established.

Your main responsibilities will include:

• Leading data collection at premier facilities, including European XFEL, SwissFEL, and MAX IV;
• Solving and interpreting time-resolved structures (SFX/SSX) from femtoseconds to milliseconds;
• Driving the biochemical characterisation of chloride transport mechanisms;
• Collaborating with international partners for spectroscopic and computational validation;
• Preparing high-impact manuscripts (previous lab work published in Science).

Required Qualifications & Experience

Please read these requirements carefully.

We will only consider candidates who meet these firm criteria:

• PhD in Structural Biology, Biochemistry, Biophysics, or a related field;
• Proven track record in protein expression, purification, and biochemical characterization;
• Strong interest in X-ray crystallography; while SFX/XFEL experience is an asset, it is not a prerequisite (full training provided);
• Fluency in English (lab language is English; no Polish required).

Desirable Skills:

• Experience with membrane proteins;
• Familiarity with serial crystallography (SFX/SSX);
• Programming skills (Python, Bash) for structural data processing.