Postdoctoral Research: Analysis of Multi-omic Datasets in Understanding Lymphopoiesis and Leukemia in Ageing

Postdoctoral Research: Analysis of Multi-omic Datasets in Understanding Lymphopoiesis and Leukemia in Ageing

IGBMC - Institute of Genetics and Molecular and Cellular Biology

Strasbourg, France

Main Activities

• Integrative analysis of epigenomic datasets derived from healthy and leukemic patients of different ages.
• Hi-C/Micro-C analysis: quantification and comparison of compartments, topologically associated domains, chromatin loops, differential interactions.
• Single-cell RNA-seq and Multi-Ome analysis; comparison with datasets from equivalent bulk methods.
• Peak calling and differential analyses from “1D” epigenomic datasets (CUT&TAG, ATAC-seq, etc.)
• Put results into context with literature searches in the hematology/oncology domains.

Associated Activities

Presentation of results in lab meetings, conferences and publications

Profil

Skills/Qualifications

• Literacy/expertise in relevant bioinformatic tools.
• Programming (R, python, etc. or equivalent).
• Background in hematopoiesis and/or oncology research.
• Ability to communicate scientific results in oral presentations and written manuscripts.

Specific Requirements or Constraints

• Good communication with “wet” researchers to coordinate the research project.
• Required Experience: 4 to 10 years
• Fields: Computational Biology, Epigenetics, Oncology
• Required Education Level or Diploma: PhD
• Required Languages: English