Upstream Processing Scientist

Upstream Processing Scientist

Formo Bio

Frankfurt am Main, Germany

Role Overview

We are looking for an Upstream Processing Scientist to support pilot-scale upstream operations and technology transfer to external manufacturing partners. The role focuses on hands-on 100L bioprocessing, scale-up readiness, and successful transfer of upstream processes to CMOs/CDMOs.

Key Responsibilities

• Execute and lead upstream bioprocess operations at the 100L pilot-plant scale, including setup, operation, monitoring, and troubleshooting;
• Design and run pilot-scale experiments to support scale-up, process characterization, and transfer readiness;
• Identify and mitigate scale-up and transfer risks related to process parameters, equipment, and raw materials;
• Prepare and maintain upstream process and technology transfer documentation (e.g., process descriptions, batch records, SOPs, protocols, and reports);
• Support technology transfer activities with CMOs/CDMOs, including remote or on-site technical support during engineering or GMP runs;
• Collaborate with cross-functional teams and communicate technical progress and risks.

About You

• M.Sc. in Biotechnology, Biochemistry, Chemical/Bioprocess Engineering, or a related field;
• 2+ years of hands-on upstream bioprocess experience at pilot scale (>10L; 100L preferred);
• Experience with microbial or mammalian upstream processes;
• Prior involvement in process or technology transfer to CMOs/CDMOs is strongly preferred;
• Strong technical documentation, hands-on mentality and excellent communication skills;
• Experience with ELNs and process risk assessments is a plus;
• Adaptability, and consistent drive for process excellence;
• Willingness to travel to support external manufacturing partners when required.