Senior Scientist Membrane Transport

Senior Scientist Membrane Transport

Constructor University

Bremen, Germany

Project overview:

The CARAMEL project aims to design boron cluster derivatives that interact with and traverse biological membranes, enabling enhanced intracellular delivery of biotherapeutics. This interdisciplinary research combines synthetic chemistry, membrane biophysics, and supramolecular interactions.

Your Responsibilities:

The selected candidate will contribute to the following tasks within the project framework:

• Design and perform multi-step synthesis of novel boron cluster derivatives, including purification and comprehensive structural characterization;
• Physico-chemical characterization of their interactions with cellular membrane models, including liposomes of different membrane composition;
• Mechanistic studies of membrane transport, employing advanced fluorescence-based assays;
• Project management and student supervision.

Your Profile:

• At least 10 years research experience after completion of a PhD in chemistry, biochemistry, or a related field;
• Strong own publication record in high-impact peer-reviewed journals;
• Solid expertise in synthetic chemistry and analytical techniques (NMR, LC-MS, HPLC, UV-vis, and fluorescence spectroscopy);
• Practical experience in supramolecular interactions, membrane biophysics, and associated techniques;
• Proficiency in written and spoken English;
• Experience in scientific writing, including articles and project proposals;
• An independent, proactive working style combined with excellent teamwork, strong organizational, time managing, and problem-solving skills.