Senior Researcher in Whole-brain Light-sheet Microscopy

Senior Researcher in Whole-brain Light-sheet Microscopy

University of Antwerp

Antwerp, Belgium

Position

You will work actively on the ERC Consolidator project “A data-driven approach to microstructure imaging” (ADAMI), funded by the European Union. ADAMI is a highly interdisciplinary project that combines insights from physics/engineering (MRI and light-sheet microscopy image interpretation), biological and medical sciences (neuroscience and brain microstructure), and computer science (machine learning and artificial intelligence) to achieve a breakthrough in predictive microstructure imaging with MRI.

Within the ADAMI project, you will help develop an innovative approach to predict the cellular composition of brain regions in MRI datasets based on in toto light-sheet microscopy of the brains of healthy and neurodegenerative mice.

You will be embedded in the Vision Lab (image processing and analysis) of the Physics Department and the Laboratory of Cell Biology and Histology (light-sheet microscopy) of the Department of Biomedical Sciences, which are within walking distance. As a postdoctoral/senior researcher, you will also help coordinate the project and assist in the supervision of PhD students.

Profile

• You hold a PhD in Biomedical Engineering, Biomedical Sciences, Physics, or a related discipline.
• You hold a FELASA certificate or are willing to obtain one, and you are willing to work with laboratory mice.
• You have a track record in processing of light-sheet microscopy data, evidenced by high-quality peer-reviewed publications.
• You have a solid understanding of the acquisition (including preparation, clearing, and immunostaining) and curation of light-sheet microscopy data.
• You can write your own image processing and analysis routines in Python, MATLAB, or C++.
• Experience with state-of-the-art artifact correction, registration, segmentation, and (shape) analysis of microscopy images—as well as integrating these steps into efficient pipelines (e.g., using bash and/or Python)—is considered a strong asset.
• Your research qualities are in line with the faculty and university research policies.
• Your teaching competencies are in line with the University of Antwerp’s educational vision.
• You act with attention to quality, integrity, creativity, and cooperation.
• You can speak and write fluently in English.