Postdoctoral Researcher - Plant Molecular Biologist in Nitrogen Fixation - PBI

Postdoctoral Researcher - Plant Molecular Biologist in Nitrogen Fixation - PBI

EIT - Ellison Institute of Technology

Oxford, United Kingdom

Your Role:

The Ellison Institute of Technology (EIT) is seeking a highly motivated and skilled Postdoctoral Researcher in Plant Molecular Biology to join its pioneering Plant Biology Institute to contribute to the ‘Biological Nitrogen Fixation’ program. This initiative seeks to engineer biological nitrogen fixation into widely grown crop plants to improve yields and reduce global reliance on synthetic fertilisers. The ultimate goal of this work will be to deliver transformative environmental, economic, and public health benefits by helping to support the transition to scalable and regenerative agricultural systems.

Your Responsibilities:

The Postdoctoral Researcher will play a key role in designing and conducting experiments aligned with stage-gated milestones in our plant engineering program. The main responsibilities of the successful candidate will be to optimise the expression, subcellular targeting, and sub-assembly and higher-order-assembly of complex enzymatic systems in plant cells using transient and stable plant transformation approaches. Successful delivery of these research objectives will require expertise in advanced microscopy techniques and imaging, plant histology, and a strong foundation in molecular biology and plant genetic engineering. Insights generated from this work will directly inform and accelerate our synthetic biology strategy to enable the introduction of novel metabolic capabilities into high-performance crop varieties.

The ideal candidate will have expertise in molecular biology and advanced microscopy techniques applied to plant tissues. This role offers a unique opportunity to conduct high-impact research at the forefront of plant science while collaborating across multidisciplinary teams to drive innovation from lab to global impact.

The postdoctoral researcher will be expected to contribute to publications and IP generation and play an active role in translating research into real-world and commercial solutions aligned with EIT’s mission of humane technological advancement. This is an exciting opportunity to develop as a scientific leader in a dynamic, well-supported, and purpose-driven environment.

Additional Responsibilities:

• Collaborate with cross-functional teams to incorporate cutting edge research techniques into experiments.
• Present scientific work at seminars within the lab and at external meetings, including contributing to laboratory-wide discussions on developments within the field.
• To assist in mentoring graduate students and other members of the research group where appropriate.
• Collaborate with experts at the forefront of research on AI, automation, and generative biology across the EIT ecosystem.
• Draft scientific papers and contribute to preparation of publications.
• To assist in the translation of scientific results into commercial opportunities consistent with the EIT humane endeavours.
• Recognising and acting on opportunities for the creation of IP and cooperating in patent protection and in impact delivery.

Requirements:

Essential Skills, Qualifications & Experience:

• Completed PhD in a relevant discipline.
• Strong research background and competency in relevant research skills or areas for the post. Examples include:
  • Demonstrated experience in advanced microscopy analysis and imaging of plant cells or tissues using light, fluorescence, and confocal microscopy techniques.
  • Demonstrated experience in plant histology including sample fixation, embedding, sectioning and histochemical staining.
  • Demonstrated experience working with a range of transient plant expression systems, including cell cultures, protoplasts, and Agrobacterium-infiltrated tissues.
  • Demonstrated experience using fluorescent reporters to visualize subcellular protein localization and to monitor cellular dynamics or metabolite levels in plant tissues.
  • Demonstrated experience in performing β-glucuronidase (GUS) reporter assays to assess promoter activity and gene expression patterns across a range of plant species and tissues.
  • Demonstrated experience in genetic engineering applied to a range of plant species, including stable transgenic approaches as well as CRISPR/Cas-mediated genome editing.
  • Strong proficiency in molecular biology, including PCR, qt-PCR, primer and construct design, molecular cloning, nucleic acid/metabolite/protein extraction, protein purification, gel electrophoresis (Agarose, SDS–PAGE, Native PAGE, Blue Native PAGE), immunodetection (e.g., Western Blot, co-immunoprecipitation), colorimetric/fluorometric plate-based assays including in vitro enzyme assays, organelle and subcellular fractionation.
  • A strong understanding of high-throughput and automated/semi-automated workflows in laboratory techniques relevant to the post.
  • Excellent skills in experimental design, data analysis, statistical evaluation, and visualisation.
• To understand (or have a desire to understand) the path to impact for the research area in question and where appropriate to consider user feedback and market research in designing research experiments.
• Demonstrated ability to conduct independent research to the highest standard, and to publish results in peer-reviewed journals.
• Ability to build both internal and external relationships. Working collaboratively with others outside of their discipline.
• Clear and demonstrable problem-solving skills.
• Excellent problem-solving, communication, and collaboration skills.
• Excellent written communication and report writing skills.

Desirable Knowledge, Skills and Experience:

• Demonstrated expertise in computational prediction, mapping, and functional characterisation of promoter sequences.
• Demonstrated expertise in measuring plant photosynthesis and performing plant growth assays under both optimal and abiotic stress conditions.
• Demonstrated expertise in plant developmental biology.