Postdoctoral Researcher - Keller-Valsecchi Team

Postdoctoral Researcher - Keller-Valsecchi Team

University of Basel

Basel, Switzerland

How does life emerge from molecules and cells? This is the central question that motivates us. 

The Keller-Valsecchi team investigates the epigenetic mechanisms and physiological relevance of gene dosage in regulating cellular function in male and female animals - from individual genes to chromosome-wide scales. We combine work in non-model organisms (like mosquitos or brine shrimp) with model systems (like Drosophila or human pluripotent stem cells) and thus are a highly diverse group.

We are seeking a Postdoctoral Researcher to join our team in an ERC-funded project. In this project, we aim to unravel sex-specific chromatin regulation across the animal tree of life by generating and integrating transcriptomes, proteomes, and epigenomes (CUT&Tag) from dozens of species.

Your position

The project

For this you will combine computational (dry lab) and experimental (wet lab) approaches. This position offers the opportunity to work at the interface of genomics, epigenetics and molecular evolutionary biology in a collaborative and interdisciplinary environment.

Your profile

• PhD in molecular biology, computational evolutionary biology, or a related life science discipline
• Expertise in bioinformatics and analysis/visualization of NGS datasets (R, command line, workflow management)
• Hands-on experience with standard molecular biology techniques (PCR, RT-qPCR, microscopy, ideally genomics)
• Knowledge of non-model genomes, genome annotation, and/or integration of multi-omic datasets (RNA-seq, chromatin profiling, chromatin accessibility, proteomics) is an asset
• Ability to work independently and drive a research project in a structured and systematic manner
• Willingness to work with non-model organisms and non-standard experimental systems
• Strong communication skills and ability to conduct projects in a team together with e.g. research assistants and undergraduate students