Analytical Scientist

Analytical Scientist

Eurofins

Rixensart, Belgium

Job Description

The successful candidate will play a key role in developing, optimizing, qualifying, and deploying robust RP-U(H)PLC and SEC-U(H)PLC analytical methods for antigen content determination and characterization in drug substance samples. This position offers the opportunity to contribute to cutting-edge biopharmaceutical development while collaborating closely with internal stakeholders’ teams.

Key Responsibilities

Method Development & Optimization:

• Design and execute experiments for RP-U(H)PLC and SEC-U(H)PLC methods, including column and mobile phase screening, gradient optimization, and sample preparation;
• Fine-tune chromatographic parameters to ensure antigen integrity, recovery, and accurate quantification.

Performance & Robustness Studies:

• Assess method accuracy, precision, linearity, sensitivity, and specificity;
• Conduct robustness studies by varying critical parameters to establish operating ranges and control limits.

Documentation & Reporting:

• Draft comprehensive Method Development Reports (MDRs), protocols, and technical input documents;
• Generate raw data packages, summary reports, and interim progress presentations for project teams.

Technical Transfer & Training:

• Support initial routine testing, troubleshooting, and knowledge transfer activities.

Deliverables:

• Final approved RP-U(H)PLC and SEC-U(H)PLC protocols and MDRs;
• Qualified methods ready for routine developmental and QC use;
• Training records confirming successful knowledge transfer;
• Comprehensive handover documentation and project summary reports.

Qualifications

• Education: The candidate should hold at least a master’s degree in Analytical Chemistry, Biochemistry, Pharmaceutical Sciences, or related field;
• Experience: A minimum of 4 years of experience with prior exposure to chromatographic method development (RP-U(H)PLC, SEC-U(H)PLC preferred).

Skills:

• Strong technical expertise in chromatography and method optimization;
• Ability to analyse complex data sets and prepare clear documentation;
• Effective communication and presentation skills;
• Collaborative mindset with willingness to mentor and train colleagues;
• Language: Fluent in English, French is nice to have.