R&D Lead Scientist

R&D Lead Scientist

Lonza

Slough, United Kingdom

What you will do:

• Design, plan, and execute studies to support technology and process development projects, analyzing complex datasets to drive conclusions;
• Evaluate and compare purification technologies to develop intensified downstream processes;
• Design, develop, and optimise scalable chromatography processes and filtration techniques;
• Perform high-throughput screening of chromatography conditions independently;
• Author high-quality technical reports and publications with scientifically supported recommendations;
• Collaborate with multi-disciplinary teams to implement technologies across development and manufacturing operations;
• Support troubleshooting and technology transfer activities, providing data-driven recommendations.

What we are looking for:

Required skills:

• Downstream process development of biologics (mAbs – monoclonal antibodies, Fc-Fusion, Bispecific antibodies);
• Process integration or connected unit operations;
• Scale-up and technology transfer of biologics.

Nice to have:

• Primary recovery techniques (centrifugation and depth filtration);
• High-throughput screening.

Other qualifications & competencies:

• Strong practical experience in protein purification techniques, including affinity, ion-exchange, hydrophobic interaction, and mixed-mode chromatography;
• Skilled in designing workflows to achieve high yield and purity, with knowledge of scale-up strategies from lab to manufacturing;
• Ability to independently plan experiments, analyze data, and communicate scientific ideas effectively;
• BSc or BEng in Biotechnology, Chemistry, or Chemical Engineering (MSc/PhD preferred);
• Business-fluent in English;
• Strong collaboration, problem-solving, and leadership skills within a scientific team environment.