Senior Scientist - mRNA Process Development (Downstream)

Senior Scientist - mRNA Process Development (Downstream)

Lonza

Geleen, Netherlands

Based in Geleen, you will take a leading role in mRNA downstream process development, owning complex purification challenges from experimental design through data interpretation. You will work with a high level of independence, while collaborating closely with multidisciplinary teams to develop robust, scalable and manufacturable mRNA processes for our clients.

What you will do

• Provide scientific and technical leadership for downstream mRNA process development activities;
• Independently design, execute and interpret complex purification experiments;
• Lead problem-solving activities and translate data into clear process improvements;
• Develop and optimize purification strategies using chromatography and filtration technologies;
• Write and review high-quality scientific reports and technical documentation;
• Support technology transfer activities and ensure processes are scalable and manufacturable;
• Collaborate with internal teams and engage with customers on downstream-related topics.

What we are looking for

• Bachelor’s, Master’s or PhD degree in biotechnology, bioengineering, chemical engineering or a related field;
• Strong hands-on experience in downstream process development for mRNA or large biomolecules;
• Advanced expertise in purification techniques such as chromatography (affinity, ion exchange, HIC, SEC) and filtration technologies, including TFF;
• Ability to independently design, execute and analyze complex experiments, including DOE-based studies;
• Proven capability to translate scientific data into actionable conclusions and process improvements;
• Experience working autonomously while contributing effectively within cross-functional project teams;
• Strong scientific communication skills, including clear reporting and presentation of results.