Postdoctoral Researcher in Computational Genomics of Alzheimers Disease

Postdoctoral Researcher in Computational Genomics of Alzheimers Disease

VIB

Antwerp, Belgium

Description

The Sleegers lab at the VIB-UAntwerp Center for Molecular Neurology Belgium, is seeking a highly motivated and talented postdoctoral researcher to work in the field of molecular and computational genomics of Alzheimer’s disease.

The Sleegers lab is an international team committed to increasing insights into the complex genetics of Alzheimer’s disease and to investigating the translational potential of genetic discovery. We have access to extensive biosample collections and use advanced omics technologies and genetic-epidemiological methods on human study populations to identify molecular mechanisms that can serve as future targets for early detection, prevention, and treatment. Our lab is at the forefront of Alzheimer’s genetics research, and has a strong international network to enhance gene identification, interdisciplinary gene characterization and early biomarker discovery.

We are seeking a highly motivated, critical and creative individual with a strong interest in computational genomics and Alzheimer’s disease to develop and/or apply computational approaches to large scale genomic or transcriptomic datasets for identification of targets for early detection, prevention or treatment of Alzheimer’s disease.

Key responsibilities

• Lead and conduct the processing and statistical analysis of large-scale long-read RNA and DNA sequencing, single nuclei RNA sequencing and spatial transcriptomics datasets;
• Use cutting-edge bioinformatics software and methods, or develop novel tools when appropriate;
• Design and lead your research project, with sufficient guidance and mentoring;
• Contribute to mentoring junior lab members and participate in grant writing and dissemination activities;
• Engage in collaborative national and international projects.

Requirements

• PhD in genetics, bioinformatics, biomedical sciences, biostatistics, or a related discipline;
• Expertise in human genomic and transcriptomic studies and a strong interest in neurodegenerative disorders;
• Programming experience, preferably in Python or R, and experience in the Linux environment;
• Solid publication record in peer-reviewed journals;
• Proficient in verbal and written English;
• Excellent teamwork, communication skills, and a commitment to advancing the field of Alzheimer genetics;
• Experience with a workflow management system such as Snakemake or Nextflow is a plus;
• Willingness to apply for an FWO Post-doc and/or Marie Sklodowska-Curie Post-doc fellowship, if eligible.