Postdoc in Translational Pharmacology

Postdoc in Translational Pharmacology

SDU - University of Southern Denmark

Odense, Denmark

The project

In the translational group, we are looking for a postdoc for a project funded by the Independent Research Fund Denmark. The project focuses on uncovering molecular mechanisms of paclitaxel-induced peripheral neuropathy (PIPN) using a novel cell culture model. The postdoc will work on a comprehensive translational research program combining advanced human iPSC-derived co-culture models, spatial transcriptomics and proteomics of patient skin biopsies, and mechanistic pathway validation. The overarching aim is to identify previously unknown molecular drivers of PIPN and explore their potential as therapeutic targets.

Your primary responsibilities:

• Lead experimental work in iPSC culture, mono- and co-culture systems, and functional neurotoxicity assays;
• Perform and coordinate transcriptomic and spatial-omic analyses in collaboration with external partners;
• Conduct CRISPRi-based pathway perturbation assays;
• Analyze and interpret complex molecular datasets in close collaboration with bioinformatic experts;
• Contribute to scientific publishing and dissemination of project results;
• Supervise students and contribute to teaching activities at SDU;
• Participate in collaborative meetings with clinical, translational, and bioinformatic project partners;
• Contribute to research group activities, including grant writing and scientific discussions.

Qualifications

We are seeking a candidate with a PhD in pharmacology, neuroscience, biomedicine, molecular biology, or a related discipline, preferably with hands-on experience in cell-based experimental work. While relevant methodological expertise is an advantage, motivation, curiosity, and a strong drive to excel in translational research are more important than any specific technical background. Excellent communication skills in written and spoken English is a requirement. The position includes independent scientific writing and supervision of students. You should be interested in contributing both to the scientific armamentarium in our department and to our collegial culture. It is also expected that the postdoc contributes to additional fundraising for the projects and takes on teaching responsibilities within the department.

You will, in your daily work, refer to Professor Tore B. Stage, but also engage in a very active collaboration with the full research group.