Postdoc Position at the Tissue Immunity Lab

Postdoc Position at the Tissue Immunity Lab

Champalimaud Foundation

Lisbon, Portugal

The selected candidate will:

The position

The Postdoc will work on a project in the research group of Dr Klaas van Gisbergen in the Tissue Immunity Lab at the Champalimaud Foundation. The aim of the project is to understand how T cells differentiate in response to local cues in solid tumors to ultimately employ this knowledge for the development of immunotherapy for improved control of cancer. The postdoc will be working on a research project and tasks will include the planning and design of experiments, supervision of co-workers, writing research manuscripts and presentation of the data at national and international conferences.

The project

In this project we aim to understand the role of tissue-resident memory T cells in immune defense against cancer. Tissue-resident memory T cells are strategically positioned in tissues instead of the circulation to quickly respond to incoming pathogens. A well-defined differentiation program imprints tissue residency in these T cells. Given recent indications that tissue-resident memory T cells are relevant to counter tumor growth, we will explore these T cells in tumor immunity using unique tools, allowing the specific visualization and manipulation of tissue-resident memory T cells. The research will be performed using state-of-the-art techniques in in vivo models, flow cytometry and transcriptional profiling.

Your profile

We are looking for an enthusiastic colleague with a PhD in Biology/Biomedical Sciences, who is highly motivated and has a proven interest in immunology and oncology. The candidate is expected to take initiative and perform well in a team and preferably has hands-on experience with animal experimentation and multi-color flow cytometry and/or transcription profiling and bioinformatics analysis. The ability to publish and present the results of your research is essential.

Skills/Qualifications:

Minimum qualifications

• PhD in Biology, Medicine, Biomedical Sciences or related areas.

Specific Requirements

Essential skills

• General skills include the ability to independently run a research project and tasks will include the planning, design and execution of experiments, supervision of co-workers, writing research manuscripts and presentation of the data at national and international conferences. Required technical lab skills include in vivo mouse experimentation, flow cytometry analysis and in vitro culture work.

Desirable skills that will also be considered

• Molecular techniques and/or fluorescence/confocal microscopy imaging and/or Bioinformatics analysis.

Languages

• English, Excellent.