Senior Researcher Whole-brain Light-sheet Microscopy

Senior Researcher Whole-brain Light-sheet Microscopy

University of Antwerp

Antwerp, Belgium

The Vision Lab of the Department of Physics in the Faculty of Sciences and the Laboratory of Cell Biology and Histology from the Department of Biomedical Sciences are looking for a full-time (100%) senior researcher in the field of whole-brain light-sheet microscopy.

Position

You will work actively on the ERC Consolidator project “A data-driven approach to microstructure imaging” (ADAMI), funded by the European Union. ADAMI is a highly interdisciplinary project that combines insights from physics/engineering (MRI and light-sheet microscopy image interpretation), biological and medical sciences (neuroscience and brain microstructure), and computer science (machine learning and artificial intelligence) to achieve a breakthrough in predictive microstructure imaging with MRI.

Within the ADAMI project, you will develop and optimize an integrated image analysis pipeline to quantify the neural and glial cell composition of brain regions using in toto light-sheet microscopy of the brains of healthy and neurodegenerative mice.

You will be embedded in the Vision Lab (image processing and analysis) of the Physics Department and the Laboratory of Cell Biology and Histology (light-sheet microscopy) of the Department of Biomedical Sciences, which are within walking distance. As a postdoctoral/senior researcher, you will also help coordinate the project and assist in the supervision of PhD students.

Profile

• You hold a PhD in Biomedical Engineering, Biomedical Sciences, Physics, or a related discipline;
• You hold a FELASA certificate or are willing to obtain one, and you are willing to work with laboratory mice;
• You have a track record in the acquisition (including preparation, clearing, and immunostaining), curation, and/or processing of light-sheet microscopy data, evidenced by high-quality peer-reviewed publications;
• You can write your own image processing and analysis routines in Python, MATLAB, or C++;
• Experience with state-of-the-art artifact correction, registration, segmentation, and (shape) analysis of microscopy images—as well as integrating these steps into efficient pipelines (e.g., using bash and/or Python)—is considered a strong asset;
• Your research qualities are in line with the faculty and university research policies;
• Your teaching competencies are in line with the University of Antwerp’s educational vision;
• You act with attention to quality, integrity, creativity, and cooperation;
• You can speak and write fluently in English.