Formulation Scientist

Formulation Scientist

Eurofins

Sittingbourne, United Kingdom

Job Description

The purpose of this job within the formulation group is to support the client in both Manufacturing and R&D efforts by conducting formulation, pre-formulation activities with analysis and characterization of the samples generated.

Job Responsibilities

• Support formulation platform screening to assess API properties and suitability for; liquid suspension, phospholipid/liposomal formulations in addition to lipid-based semi-solid or liquid in capsule formulations;
• Practical support for small scale manufacturing and pre-formulation activities for the development of drug product batches to be utilized in oral solid dosage forms, including planning, execution (including set up and clean down) and writing up of lab work. Examples may include but not limited to Spray drying, solvent injection, roller compaction, blending, tablet compression, coating, encapsulation as well supporting in-use stability activities;
• Product and Materials characterization support (including techniques such tablet characterization, Particle Size Analysis, powder flow, and bulk properties of formulations such as rheology and polymer characterization);
• Interpretation of data and contributing to writing internal development protocols and reports;
• Write laboratory reports ensuring accurate and timely data reporting and analysis is maintained;
• Supporting design, prototype and scale up of drug product formulations and manufacturing processes;
• Provide technical support to downstream activities, including product control strategy, technology transfer and launch, and relevant protocols and reports;
• Equipment and instrumentation ownership, assisting with the maintenance, upkeep and calibration;
• Assist in wider scientific capability development, via relevant internal technical networks, and ongoing Technology initiatives;
• Research, compile and summarise information from multiple sources (internal reports, pharmacopeia, scientific literature, handbooks etc) to inform gap analysis and formulation development;
• Conduct analysis using fully electronic media including e Notebook;
• Support continuous improvement processes;
• Perform and assist in additional duties as directed by the client contact;
• Familiarisation with electronic lab notebooks and ALCOA principles for the recording of data;
• Write or constructively review SOP’s, Protocols, technical reports, risk assessments as required.

Qualifications

• A degree in Chemistry or a related discipline is required;
• A sound, fundamental knowledge and practical application of Organic Chemistry to pharmaceutical drug design is essential;
• Appropriate relevant experience of Material Science and analytical tools and techniques within a group organisation;
• Good foundation and experience with traditional analytical techniques as well as modern instrumental equipment (e.g., Particle size, PXRD, DSC, TGA). Must possess sound knowledge of analysis methods and tools.