Cell Engineering Manager

Cell Engineering Manager

Evotec

Toulouse, France

As a Cell Engineering Manager at Just Evotec Biologics, you'll have the freedom to ask the hard questions, think outside the box, and find creative solutions that push us forward. It’s a role where your curiosity will fuel both your personal growth and the success of the team.

What You’ll Do:

• Lead and grow a team including Scientists and Associate Scientists in cell engineering to support all aspects from pre-clinical through late stage development.
• Optimize strategies, and workflows that increase efficiency and de-risk projects.
• Lead efforts to identify, evaluate and promote new cell engineering technologies to support the mission of low cost biotherapeutics.
• Collaborate across the organization and be a key member and contributor to the Process and Product Design Leadership Team.
• Be a technical resource on cell engineering for novel biologics and biosimilars for Discovery, Process Design, Quality, and Manufacturing, as well as a resource and subject matter expert for clients, service providers and collaborators.
• Serve as a cell engineering lead for complex projects and/or oversee leads on cross-functional project teams.
• Manage and develop staff, and manage resource planning.
• Develop and refine cell engineering strategies that incorporate best practices and align with evolving regulatory expectations.
• Support successful MCB and WCB manufacturing for client projects.
• Ensure compliance with EHS practices and the company's CSR policy.
• Represent Just-Evotec Biologics at external meetings and conferences.

Who You Are:

• Expert in cellular biology techniques to create stable cell lines suitable for protein therapeutics.
• Strong expertise in cell line engineering for protein therapeutics including experience with a multiple mammalian cell lines.
• Experience with expression construct design for cell lines expressing large molecules, such as mAbs, fusion proteins, and bi-specifics.
• Proficiency creating novel expression vectors to obtain highly productive cell lines that express material to meet process development product quality targets.
• Experience in cell line engineering for commercialization of novel biologics and biosimilars, including experience designing cell lines to match innovator PQA/CQA.
• Proficiency in regulatory guidelines and best practices for filing IND/IMPD/BLA/MA sections.
• Experience utilizing high throughput automation and data systems.
• Experience in management with the ability to work collaboratively and flexibly in a team environment with other functions to solve problems and deliver on projects.
• Experience with resource planning tools, and allocation and tracking of resources and equipment.
• Excellent written and verbal communication skills, with expertise communicating effectively over teleconference and web-based meetings.
• People-oriented and team player.
• Diploma: Ph.D. preferred in a relevant field (e.g. biochemistry, chemistry, chemical engineering) or Master in Science.
• Experience: 10+ years (Ph.D.) or 15+ years (MS) of experience, or equivalent experience in the biotechnology or biopharmaceutical industry.