The project aims to develop novel anti-biofilm compounds that can be used to treat biofilm-related infections caused by a range of bacterial pathogens. Based on structural data demonstrating how an existing anti-biofilm compound binds to and activates its specific target in Pseudomonas aeruginosa, we will design, develop and test novel anti-biofilm compounds with broader activity against the WHO priority pathogens Escherichia coli, Klebsiella pneumoniae and Acinetobacter baumannii. You will be working in a trans-national research consortium including experts in structure-based modelling, structure biology and chemistry.
PhD in Molecular Biology, Microbiology, Biochemistry or Structural Biology with research experience in any of these areas. You are highly motivated, organized, independent, flexible, with excellent communication and strong team-player skills.