Senior Scientist Applications - Pathogen

Senior Scientist Applications - Pathogen

EIT - Ellison Institute of Technology

Oxford, United Kingdom

We are seeking a highly skilled and innovative Senior Scientist to join our Applications team, focused on developing cutting-edge diagnostic tests for infectious diseases. The role emphasises metagenomics but also includes a range of sequencing and non-sequencing-based approaches. Ideal candidates will have strong experience with sequencing technologies, and a proven track record of developing end-to-end clinical diagnostic applications in either academic or industrial environments.

In this position you will work with a small agile team to to deliver prototype diagnostic assays in a fast-paced, start-up-like environment. Strong problem-solving, troubleshooting, and molecular biology skills are essential.

Key Responsibilities

• To research, design and prototype diagnostic assays for important infectious disease syndromes (e.g. respiratory tract infections) using the latest sequencing technologies (long and short read);
• To work with internal and external stakeholders to identify innovative approaches to simplify and reduce time and cost of metagenomic diagnostic approaches, from sample collection to result;
• Work closely with experts to automate diagnostic assays, leading to cost-effective, easy to use tests;
• Work closely with AMR, Informatic and Machine Learning colleagues ensure the tests provide accurate pathogen ID, AMR and relatedness results;
• Engage with industry and academic experts to identify and assess promising new technologies relevant to the aims and objectives of the team.

Essential Knowledge, Skills, and Experience

• A PhD in a relevant scientific discipline (e.g. molecular biology, genomics, microbiology, virology or a related field);
• In-depth expertise in genomics and/or metagenomics;
• Strong foundation in molecular biology techniques and applications;
• Demonstrated experience in laboratory operations and personnel management;
• A proven track record of achievement in academic and/or industrial research settings;
• Hands-on experience in the design, development, and prototyping of molecular assays, particularly in areas such as infectious diseases, oncology, human genetics, plant or food pathogens, or veterinary diagnostics;
• Experience collaborating within multidisciplinary teams, with the ability to effectively communicate across scientific domains.

Desirable Knowledge, Skills, and Experience

• Background in microbiology, virology and/or infectious diseases;
• Familiarity with clinical metagenomics applications and workflows;
• Foundational skills in bioinformatics, particularly in the analysis of genomic or metagenomic data.

Key Attributes

• Innovative thinker with a proactive approach to problem-solving and technology development;
• Strong troubleshooting skills, with the ability to identify and resolve complex technical issues;
• Highly organised, with excellent time management and prioritisation abilities;
• Effective communicator with strong presentation skills and a proven track record of delivering to diverse audiences;
• Demonstrated ability in technology horizon scanning and staying abreast of emerging scientific trends;
• Proven leadership skills, with experience guiding teams and driving projects to successful outcomes.