Postdoctoral Position in Biological Validation of Mechanobiological Platforms for Therapeutic Innovation

Postdoctoral Position in Biological Validation of Mechanobiological Platforms for Therapeutic Innovation

IMDEA Materials Institute

Madrid, Spain

SHORT DESCRIPTION

IMDEA Materials is looking for a highly motivated postdoctoral researcher to join a regional research initiative funded by the Community of Madrid. The selected candidate will work at the intersection of experimental biology, materials engineering, and computational modeling (digital twins). The project’s goal is to transform mechanobiology into a key engine of innovation in healthcare, deepening the understanding of disease mechanisms while paving the way for new therapeutic strategies and translational applications. This will be achieved through the use of cutting-edge technological platforms such as advanced in vitro systems, organ-on-chip models, and bioengineered scaffolds.

Description

The postdoc will lead research on the biological evaluation of mechanobiological lab-on-chip and digital twin systems, with a focus on designing and executing innovative experiments. The work will include defining and optimizing in vitro models using diverse cell types and advanced platforms, as well as establishing correlations between applied mechanical stimuli, cellular responses, and underlying biological pathways and mechanisms. The ultimate goal is to decipher disease processes, propose novel therapeutic strategies, and harness mechanobiological cues for applications in tissue engineering and regenerative medicine.

Requirements

• Candidates should hold a PhD in biomedical engineering, biology, chemistry, medical science, biotechnology, or a related discipline;
• Experience in cellular and molecular biology and/or tissue engineering;
• Strong expertise in advanced cell culture systems (3D cell culture: organoids/spheroids, scaffolds);
• Experience with mechanobiology techniques (mechanical stimulation, bioreactors, microfluidics) (Desired);
• Good communication skills;
• Fluent English (written and oral);
• Confident at being hands-on in the lab and an excellent self-starter;
• Quick learner and comfortable working in novel environments;
• Ability to design, execute, and supervise experiments independently;
• Experience in mentoring students and working in multidisciplinary teams;
• Availability for incorporation in January 2026.