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The specific project you will be involved in aims to further elucidate the functionality of SOX2, whose molecular regulation is a long-standing interest of the lab and which we recently discovered to be involved not only in transcription, but also in
This researcher will contribute to a highly interdisciplinary project that explores microbial enzymes as promising antimicrobial drug targets. The successful candidate will dissect enzyme function through biochemical characterization, conduct inhibitor
You will add viruses to a global ecosystem model (MIT’s DARWIN model), coupled to an ocean circulation model (MITgcm). The model will use a trait-based approach both for the viruses and the phytoplankton. Specifically, using information on
Directly execute ex vivo genome editing experiments in primary stem cells using base and prime editing; Perform functional in vitro assays to assess stem cell identity, differentiation, and regenerative potential; Generate and analyze