PostDoc in Biotechnology/Protein Biochemistry (Spider Silk)

PostDoc in Biotechnology/Protein Biochemistry (Spider Silk)

SLU - Swedish University of Agricultural Sciences

Uppsala, Sweden

Come join our spider silk team! In this project we will develop novel methods for producing recombinant spider silk proteins. As a research group we are interested in how spiders have solved problems related to protein production, storage and polymerization, and develop methods for producing the material by recombinant protein production and biomimetic fiber spinning. The group consists of an excellent team of several PhD students, PostDocs, and Researchers working on different projects related to biotechnological methods for producing recombinant silk proteins, characterization of these, spinning of fibers, protein engineering, material characterization and bioinformatics to understand the transcriptome profile of the silk glands. The atmosphere in the group is ambitious, innovative, and friendly. In order to develop our production methods further, we are looking for a postdoc with a keen interest in biotechnology and protein biochemistry.

About the position

Your work will involve the use of several different heterologous hosts to improve our current production methods of spider silk proteins, primarily focusing on prokaryotic systems, but potentially extending to yeasts and cell lines. The candidate is also expected to independently develop efficient protein purification methods. Protein engineering and characterization of the produced proteins by SDS PAGE, CD spectroscopy, FTIR spectroscopy, rheology and SEC are also part of the work.

The applicant is expected to pursue the project actively, keep updated with the literature, interact with the other team members, be active at journal clubs and meetings, present results pedagogically, write reports and papers, and have a positive attitude. You will be responsible for planning, executing and analysing data and should enjoy working in a vibrant and collaborative atmosphere. Excellent knowledge of English is a requirement (at least C1 level in reading, writing, and listening). If you apply from outside Europe and are not a native English speaker, a certificate verifying your skills in English (listening, reading, and writing) is required.

Your profile

A PhD in a relevant field obtained within the past five years, along with several publications in international peer-reviewed journals, including at least one as first author, is required. Extensive previous practical experience in the following is required and should be clearly described in the personal letter:

• Protein expression in prokaryotes and/or yeasts;
• Experience with multiple protein purification techniques;
• Development of recombinant protein production protocols;
• Proficiency in at least two methods for protein characterization.

As a person you are positive, efficient, ambitious, thorough, enjoy lab work, and able to keep deadlines.

The appointment will be offered to the applicant who, following a qualitative comprehensive assessment, is deemed to have the best skill set to conduct and develop the duties in question and contribute to the positive development of the organisation.

Apply NowDeadline 17 August