Research Fellow in Analytical Chemistry
Research Fellow in Analytical Chemistry
Trinity College Dublin
Dublin, Ireland
Post Summary
Our research group is investigating skin allergy related to medical devices. Continuous glucose-monitoring devices and insulin pump systems have become an essential component of the management of diabetes, a chronic disease that affects over 500 million people worldwide. As the prevalence of diabetes increases, the use of these devices is also expanding. These devices are affixed to the patient’s skin using an adhesive patch. Allergic contact dermatitis (ACD) to components of glucose-monitoring sensors and insulin pumps is increasingly problematic as disease management becomes dependent on wearable technologies.
The objective of this project is to analyse the chemical composition of diabetic medical devices to understand what allergenic chemicals are present, focusing on emerging skin allergens. We expect to establish the identity and quantity of skin allergens present in devices currently used by patients. In line with best practice, we will take a dual approach and patch- test patients presenting with skin allergy to these devices to identify the clinically relevant allergens. This will allow us to counsel patients on the best strategy for avoiding skin allergy to their medical devices. Identification of skin allergens will also provide valuable information to the manufacturers of these devices to enable replacement of currently used chemicals with better, less toxic alternatives.
The principal techniques used in this project will be gas chromatography/mass spectrometry (GC/MS), liquid chromatography/mass spectrometry (LC/MS), and high-performance liquid chromatography (HPLC). The work will involve collaboration with clinical colleagues at South Infirmary Victoria University Hospital, Cork, Dept of Paediatrics, Cork University Hospital and University College Cork.
Standard Duties and Responsibilities of the Post
The purpose of this role is to conduct a specified programme of research related to analysis of glucose-monitoring devices under the supervision of Dr. O’Boyle and Dr. Bourke. The work will be performed in accordance with the university’s research integrity policy and all other relevant policies.
The successful candidate will:
- Conduct research developing analytical methods and analysing the chemical composition of glucose monitoring devices to the highest standard;
- Carry out any administrative work associated with the programme of research;
- Engage in the dissemination of the results of the research for the relevant research stakeholders and general public;
- Provide day-to-day advice and assistance to research graduate students associated with the research group.
Person Specification
The successful candidate will have the necessary technical skills for the project, together with organisational skills an ability to plan experiments, analyse data and write reports.
Qualifications
- Minimum of PhD in analytical chemistry or a closely related area.
Knowledge & Experience (Essential & Desirable)
Essential:
- Experience in mass spectrometry is essential for this role;
- Good communication and interpersonal skills with the capability of working within a project team to achieve results.
Desirable:
- Experience in GC/MS method development and quantification is an advantage;
- Record of scientific publication and presentation at scientific conferences;
- Previous postdoctoral experience.
Skills & Competencies
- Demonstrates knowledge of a research discipline and field, and the operational requirements of a successful research project;
- Demonstrates the ability to generate new ideas and link and build upon existing ideas to generate unique concepts and solutions with integrity;
- Demonstrates evidence of research activity and a commitment to ongoing research and publications;
- Demonstrates an ability to manage self, time, and own resources to enable a high level of personal effectiveness.
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