Research Engineer in the Tumor Immunotherapy and Microenvironment (TIME) Group

Research Engineer in the Tumor Immunotherapy and Microenvironment (TIME) Group

LIH - Luxembourg Institute of Health

Luxembourg

Key Accountabilities

As a Research Engineer, you will play a key role in supporting ongoing research activities within the group. Your responsibilities will include:

• Conducting wet lab experiments in cell and molecular biology, radiation biology, biochemistry, and tumor biology;
• Supporting in vitro (2D and 3D cell cultures) and in vivo (mouse) experiments;
• Performing irradiation with X Ray (Centre Baclesse – Luxembourg) and High-LET particles (CNAO – Italy);
• Performing cell survival analysis, DNA double-strand break analysis, radiosensitization, analysis of cell cycle response and gene expression analysis;
• Applying immunostaining, microscopy (e.g., confocal), western blotting, qPCR, and flow cytometry;
• Manage and analyze large-scale RNA-seq datasets; proficiency in bioinformatics and R is a strong asset;
• Training and mentoring junior staff and trainees;
• Participating in lab meetings and scientific discussions;
• Contributing to the development and implementation of novel experimental techniques;
• Supporting general lab organization and maintenance;
• Writing scientific reports and presentations for internal and external dissemination;
• Participating in bibliographic research and applying findings to optimize lab protocols.

Key Skills, Experiences and Qualifications

Education & Experience:

• Master’s degree in biology, cancer biology, or a closely related field. Candidates with a Bachelor's and strong relevant experience will also be considered;
• Minimum 2 years of hands-on experience in a cancer biology or related research environment.

Technical Skills:

• Knowledge of tumor biology and radiotherapy;
• Proficiency in molecular and cellular biology techniques;
• Knowledge in radiation therapy, cell survival and DNA double-strand break techniques;
• Experience with in vivo mouse models (FELASA or equivalent certification);
• Ability to handle and analyze large-scale omics data;
• Experience with gene cloning.

Soft Skills:

• Strong sense of initiative, rigor, and motivation;
• Excellent organizational and prioritization skills;
• Ability to work independently and collaboratively in a multidisciplinary team;
• Excellent problem-solving and critical thinking abilities;
• Fluent in English (spoken and written); knowledge of another EU language is an asset;
• Willingness to adapt working hours to project needs and travel within the EU.

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