Artificial evolution is a powerful method that makes it possible to isolate nucleic acids with specific functions (such as the ability to bind a ligand or catalyze a reaction) from large nucleic acid libraries. The group of Dr. Edward Curtis at IOCB Prague uses this method for a variety of projects, including to isolate catalytic DNA molecules (deoxyribozymes) that generate chemiluminescent, fluorescent, and colorimetric signals and to identify RNA-cleaving deoxyribozymes from structured nucleic acid libraries. The group is searching for a postdoc with a background in bioinformatics who will help to process and analyze high-throughput sequencing datasets generated in these experiments.