Post-Doctoral Fellow in Pancreatic Cancer Research

Post-Doctoral Fellow in Pancreatic Cancer Research

Champalimaud Foundation

Lisbon, Portugal

We are seeking a highly motivated and skilled Post-Doctoral Fellow to join our dynamic research team at the Botton-Champalimaud Pancreatic Cancer Centre.

This prestigious center is dedicated to advancing pancreatic cancer research and treatment through innovative approaches and multidisciplinary collaboration. The successful candidate will contribute to cutting-edge research aimed at understanding the molecular mechanisms of pancreatic cancer progression and developing novel therapeutic strategies.

Working within this state-of-the-art facility, you will have access to advanced technologies and a network of world-renowned experts in the field of pancreatic cancer.

The successful candidate will work within the Cancer Genome and Evolution laboratory led by Professor Vincenzo Corbo.

Duties and Responsibilities

• Design and conduct experiments to investigate pancreatic cancer biology, including tumor heterogeneity, cell signaling pathways, tumor microenviroement, and drug resistance mechanisms;
• Develop and optimize in vitro and in vivo models of pancreatic cancer;
• Generate and maintain patient-derived organoids for pancreatic cancer research;
• Utilize patient-derived organoids to study drug responses, tumor heterogeneity, and personalised treatment approaches;
• Analyze and interpret complex experimental data using advanced statistical and bioinformatics tools;
• Present research findings at team meetings, conferences, and scientific symposia;
• Prepare manuscripts for publication in peer-reviewed journals;
• Collaborate with other researchers and clinicians within the Botton-Champalimaud Pancreatic Cancer Centre and external partners;
• Mentor and supervise junior researchers and graduate students;
• Contribute to grant writing and funding applications;
• Participate in translational research initiatives to bridge laboratory findings with clinical applications;
• Engage in knowledge exchange and public outreach activities to promote pancreatic cancer awareness and research;
• Prepare Standard Operating Procedures (SOPs) for laboratory techniques and experimental protocols;
• Contribute to the development and maintenance of quality management systems within the research facility.

Requirements

• Research Field: Biological sciences;
• Education Level: PhD or equivalent;
• Excellent lever of English;
• 1 to 4 years of experience.

Skills/Qualifications

Key Skills

• Problem solving;
• Flexibility;
• Attention to detail;
• Organisation;
• Initiative.

Specific Requirements

Essential Criteria

• Ph.D. in Cancer Biology, Molecular Biology, Biochemistry, or a related field;
• Strong background in cancer research, preferably with experience in pancreatic cancer, pancreatic neuroendocrine cancer and RNA biology;
• Expertise in molecular biology techniques, cell culture, and animal models;
• Proficiency in data analysis, bioinformatics, and statistical methods using R or Python or equivalent language;
• Excellent written and verbal communication skills;
• Demonstrated ability to work independently and collaboratively in a multidisciplinary environment;
• Track record of scientific publications in peer-reviewed journals.

Preferred Skills

• Experience with advanced imaging techniques (e.g., confocal microscopy, live cell imaging);
• Familiarity with next-generation sequencing and multi-omics data analysis;
• Experience in data analysis using R and/or python;
• Knowledge of drug discovery and development processes;
• Experience with grant writing and securing research funding.

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