Postdoc in Vivo Work Beta Cell Research

Postdoc in Vivo Work Beta Cell Research

Leiden University Medical Center

Leiden, Netherlands

Breakthroughs in diabetes research start with pioneering studies on insulin-producing cells. At LUMC, you will work as a postdoc in vivo work beta cell research in a leading center with unique expertise in this field. Surrounded by more than a hundred stem cell researchers in the state-of-the-art laboratories of Mirai House, you will contribute to the development of innovative stem cell therapies. You will combine experiments with in-depth analyses and scientific publications, making a direct impact on new treatment methods. An opportunity to merge science and innovation at the forefront of translational research.

About your role

As a postdoc within the Islet group of the Department of Internal Medicine, you will work on translational research focused on the transplantation of primary human pancreatic and stem cell-derived insulin-producing cells. You will be part of the in vivo team and contribute to research aimed at developing new treatments for diabetes mellitus. Additionally, you will support the isolation of islets of Langerhans within a GMP environment, a process that may involve irregular working hours.

Your top five tasks:

  • Conducting transplantation experiments with primary human pancreatic and stem cell-derived insulin-producing cells in immunodeficient mice or rats;
  • Analyzing the survival, integration, and function of the transplanted cells;
  • Supporting the isolation of islets of Langerhans for both transplantation and research purposes;
  • Collaborating with internal and external partners in the research field;
  • Reporting research findings in scientific publications and presentations.

About you

You have a strong interest in both fundamental and translational research and experience working with animal models. You are well-organized, accurate, and thrive in a collaborative team environment. Additionally, you have strong teamwork skills and an excellent command of the English language.

Furthermore, you have:

  • A PhD in a relevant field, such as cell biology or biomedical sciences;
  • Article 9/12 certification and experience working with rodent models;
  • Knowledge of and experience with various molecular and cellular techniques, including cell culture, flow cytometry, qPCR, western blot, (immuno)histochemistry, and microscopy;
  • A structured and precise work approach;
  • Flexibility and a willingness to work irregular hours.

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