Postdoctoral Researcher in Oncohematology

Postdoctoral Researcher in Oncohematology

IEO - European Institute of Oncology

Milan, Italy

The Laboratory of Oncohematology, coordinated by Prof. Enrico Derenzini, MD, at the Department of Experimental Oncology (DEO) of the European Institute of Oncology (IEO), is looking for a highly motivated postdoctoral researcher.

Our research group operates at the interface between clinical and basic/translational research, aiming to elucidate the molecular mechanisms underlying difficult-to-treat hematological malignancies and to develop novel pharmacological treatments and immunotherapy strategies. Our primary objective is to rapidly translate preclinical discoveries into precision-therapy clinical trials and identify biomarkers predictive of treatment response.

Our main research focuses on:

• Identifying specific vulnerabilities in chemoresistant lymphomas and leukemias to develop novel synthetic lethality-based therapies, with a focus on MYC, BCL-2, MCL-1, and DNA repair mechanisms;
• Developing innovative strategies to enhance the efficacy of current immunotherapies, including CAR-T cells, dendritic cell vaccination, and NK-cell therapy.

The successful candidate will work in close collaboration with both clinical and basic researchers and will actively contribute to the lab’s key projects.

Required qualifications:

• Master’s degree in Biology, Biotechnology, Pharmacology, or related fields;
• PhD in Biology, Biotechnology, Oncology, Genetics, Pharmacology, Molecular Medicine, or a related discipline;
• Previous experience in a biomedical research environment;
• Proficiency in cellular and molecular biology techniques;
• Experience with in vivo experiments using murine models (preferred but not mandatory);
• Strong sense of responsibility, precision, and independence in research activities.

Additional desirable qualities:

• Excellent organizational and problem-solving skills;
• High level of motivation, reliability, and precision;
• A collaborative and open-minded approach to teamwork.

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