Research Assistant: Single-cell Genomics Platform

Research Assistant: Single-cell Genomics Platform

University of Basel

Basel, Switzerland

Your position

  • Isolate and prepare single cells from various eye tissues and cultures; perform advanced NGS library preparations, including RNA-seq, Epi Multiome, and CITE-seq using 10x Genomics platforms.
  • Prepare sequencing libraries and operate sequencing instruments such as Illumina and ONT (Oxford Nanopore Technologies).
  • Develop and implement innovative plate-based (e.g., FLASH-seq) and emulsion-based protocols for specialised NGS applications in collaboration with IOB researchers.
  • Contribute to the establishment, optimisation, and implementation of Spatial Transcriptomics methodologies.
  • Maintain and ensure the quality and consistency of existing NGS protocols.
  • Provide technical assistance and expert guidance to IOB researchers for their projects.

Your profile

  • Master's degree (or equivalent) in Molecular Biology, Biotechnology, or a related field, with substantial hands-on experience in NGS workflows.
  • Proven work experience in cell biology is advantageous.
  • Demonstrated expertise in executing NGS protocols is essential.
  • Familiarity with liquid handling robotic platforms (e.g., Tecan) and automated dispensers (e.g., I.DOT) is desirable; training will be provided if required.
  • Proven ability to independently plan, execute, and troubleshoot NGS experiments.
  • Strong multitasking skills with the ability to manage and prioritise multiple parallel tasks effectively.
  • Willingness to acquire and apply new technical skills on cutting-edge instruments as needed.
  • Passion for developing, refining, and optimising new protocols and experimental techniques.
  • Highly organised, with exceptional attention to detail.
  • Fluency in oral and written English is required.

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