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Design and perform genetic and genomics screens to reconstruct maps of functional interactions across the ERN; Design and carry out functional experiments to mechanistically dissect the basis of identified interactions; Identify physiologically relevant
Develop a comprehensive and cutting-edge experimental approach to interrogate the ERN; Design and perform advanced genetic and genomics screens to reconstruct maps of functional interactions across the ERN; Design and carry out functional experiments to
The successful candidates will contribute to projects aimed at identifying molecular mechanisms of tumor aggressiveness and discovering clinically relevant biomarkers and therapeutic vulnerabilities in epithelial cancers, with a particular focus on breast