Senior Statistician

Senior Statistician

C4X Discovery

London, United Kingdom

The Company

C4X Discovery (C4XD) is currently looking for a Senior Statistician to join their Human Genomics team to develop data-driven precision medicine strategies for complex inflammatory diseases such as rheumatoid arthritis and IBD.

C4XD is a pioneering Drug Discovery company combining scientific expertise with cutting-edge technologies. Our commercially attractive portfolio ranges from early-stage target opportunities to late-stage Drug Discovery programmes and we have three commercially partnered programmes with one candidate in clinical development.

The Role

The role aims to enhance the capability of the existing team as our drug discovery portfolio grows and we develop the opportunities for patient stratification in immuno-inflammatory diseases.

The Human Genomics team at C4XD is a multidisciplinary group of Data Scientists and Bioinformaticians who work with genetics and multimodal datasets to provide data-driven insight for complex diseases to advance drug discovery and precision medicine within C4XD. PatientSeek is C4XD’s precision medicine platform, which applies the unique mathematical approach of Taxonomy3^® to stratify patients for novel treatments based on their genetics with multi-modal phenotypic data.

This role is a hybrid-based role.

Responsibilities

The main responsibilities of the role will include:

• Statistical modelling of biological and clinical datasets, including longitudinal measures, using an appropriate statistical programming language (e.g., R/python);
• Provide expert knowledge to support and improve the underlying mathematical principles of the PatientSeek and Taxonomy3 methodology;
• Propose and develop new analytical features for the PatientSeek precision medicine platform;
• Co-ordinate with other researchers in C4XD and external collaborators to ensure the projects progress smoothly and efficiently;
• Communicate results to the wider C4XD organisation;
• Ensure record keeping and archiving of data is up to date and accurate;
• Ensure C4XD and external data privacy policies are adhered to;
• Support business development activities when required;
• Support reputational building with publications and poster and oral presentations at conferences;
• Support appropriate protection of genetic and biological intellectual property.

Education, Experience & Skills Required

Essential:

• Ph.D. (or M.Sc. + relevant experience) in mathematics or statistics;
• Experience working with Electronic Health Records or Real World Evidence/Data;
• Experience modelling longitudinal biological or clinical data;
• Knowledge and understanding of Bayesian statistical methods;
• Knowledge and understanding of data privacy issues and requirements;
• Experience with IT tools (e.g., cloud computing, AWS, Linux, HPC), programming languages (e.g., R, Python, SQL, bash), and version control management (e.g., git);
• Highly self-motivated, flexible and organised;
• The ability to work independently but know when additional input is required;
• Excellent communication and presentation skills;
• Creative thinking and enthusiasm for innovation.

Desirable:

• Knowledge of immuno-inflammatory diseases (e.g., rheumatoid arthritis, IBD);
• Understanding of biology/human genetics/bioinformatics;
• Experience working in a multi-disciplinary team in a biotech or pharma setting.

Benefits

C4X Discovery offers a broad selection of health benefits, share options, enhanced family leave, a generous pension scheme and an annual, discretionary bonus scheme.

We encourage applications from individuals of all backgrounds, ethnicity, gender identity, sexual orientation, disability, neurodiversity, age, family or parental status, beliefs, nationalities and religions - supporting an inclusive environment for all our colleagues to bring their true selves to C4XD.

Apply Now

More Job Searches

United Kingdom      Biology      Biotechnology and Genetics      Commercial      Computing/Programming      Mathematics      Maths and Computing      Statistics      C4X Discovery