Technician/Sr. Technician - Bienko Group, Genomics Research Centre

HT - Human Technopole

Technician/Sr. Technician - Bienko Group, Genomics Research Centre

HT - Human Technopole

Milan, Italy

Job description


Human Technopole (HT) is a new interdisciplinary life science research institute, created and supported by the Italian Government, with the aim of developing innovative strategies to improve human health. HT is composed of five Centres: Computational Biology, Structural Biology, Genomics, Neurogenomics and Health Data Science. The Centres work together to enable interdisciplinary research and to create an open, collaborative environment that will help promote life science research both nationally and internationally.

The Bienko Group at HT ( focuses on understanding the fundamental principles that regulate how chromatin is spatially organized in the nucleus of mammalian cells and how the three-dimentional (3D) organization of the genome is affected by alterations in its sequence, such as those commonly encountered in human cancers.

The group is now inviting outstanding candidates with an excellent background in molecular biology/biotechnology and proven track record in various laboratory techniques to apply for a position as Technician or Senior Technician depending on the candidate’s level of experience.

The successful candidate will be embedded in a multi-cultural and interdisciplinary team and take part in the lab’s efforts in engineering cells with rewired karyotypes, studying the effects of karyotypic changes on genome architecture and gene expression, and developing new methods to study the 3D genome in single cells.

She/he will have the following responsibilities:

  • Support the initial setup of the laboratory at the Human Technopole;
  • Support the group in various tasks, including but not limited to: (i) overseeing reagent and small equipment purchases; (ii) setting up and maintaining a lab reagent inventory; (iii) setting up and maintaining working routines; (iv) networking with facilities at HT;
  • Perform standard molecular/cell biology tasks (e.g. PCR, tissue culture);
  • Lead the implementation of various NGS-based methods and DNA/RNA FISH;
  • Train other members of the lab in performing standard experimental methods;
  • Record data and protocols in a detailed and well-organized electronic form;
  • Apply various methods established by the Bienko Group in the frame of scientific collaborations with other research groups nationally and internationally.

Job requirements

Essential requirements:

  • M.Sc. or Ph.D. degree in Molecular Biology, Biotechnology, Biomedicine, or equivalent;
  • Extensive theoretical knowledge and documented hands-on experience in mammalian cell culture/transfection/transduction and basic molecular biology/biochemistry/microscopy techniques (DNA/RNA purification, PCR, reverse transcription, in vitro transcription, cloning, western blotting, widefield and/or confocal immunofluorescence microscopy);
  • Proficiency with various omic methods that are particularly relevant to the research focus of the group (e.g., RNA-seq, ChIP-seq, ATAC-seq, Hi-C) and/or with CRISPR-Cas technologies will be considered a strong advantage.

Additional desired requirements:

  • 5 years of experience from wet lab;
  • Strong experience in molecular biology techniques;
  • First author publication in the field of genomics/epigenetics;
  • Experience from working abroad.

Required personal skills:

  • Ability to independently organize her/his own work routine and to flexibly adapt her/his weekly schedule to emerging requests;
  • Strong problem-solving and forward-looking personality, i.e., she/he is motivated to solve obstacles that might present on the path to achieving a goal, enjoys troubleshooting, is not afraid of seeking for help, and strongly believes that a solution to a problem can be found even if this means revising the original goal/plan (never compromising scientific rigor and quality);
  • Strong collaborative attitude, i.e., she/he is a strong team player and feels that the success of the whole team will only come from all its members being actively engaged and helping each other;
  • Fluency in oral and written English;
  • Special consideration will be given to candidates who are part of the protected categories list, according to L. 68/99.

Application information

Please apply by sending a CV and a 1-page motivation letter in English only through the dedicated area below (Apply now) and the name and contact details of at least 2 potential referees. In the motivation letter, please emphasize your prior lab work and how you think you can contribute to the success of the Bienko Group and Human Technopole.

For specific enquires concerning the role only, please contact Magda Bienko, Group Leader:

Additional information

HT offers a highly collaborative, international culture to foster top quality, interdisciplinary research by promoting a vibrant environment consisting of independent research groups with access to outstanding graduate students, postdoctoral fellows, and core facilities.

HT is an inclusive employer that fosters diversity and engages systematically to ensure that equal employment opportunities are provided without regard to age, race, creed, religion, sex, disability, medical condition, sexual orientation, gender identity or expression, national or ethnic origin or any other legally recognized status entitled to protection under applicable laws. HT offers attractive conditions and benefits appropriate to a leading, internationally competitive, research organization that promotes a collegial and open atmosphere and favors flexible and person-tailored working conditions to balance work with personal life.

The Human Technopole Foundation is based in Milan, recently named the city with the best quality of life in Italy (

Number of positions offered: 1
Contract offered: CCNL Chimico Farmaceutico, Employee level, contract duration 5 years.

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