Group Leaders - Functional Genomics

HT - Human Technopole

Group Leaders - Functional Genomics

HT - Human Technopole

Milan, Italy

Job description


We are seeking talented, preferably early career, researchers to establish their independent laboratory at the HT Centre for Functional Genomics. Exceptionally, we will also consider mid-career leading scientist that are considering to move to HT. The Research Group Leaders will be responsible for developing an independent scientific programme within the Centre, as well as contributing to the collegial development of the HT research programme. They will be active researchers carrying out high-quality, internationally competitive research and contributors to the international scientific community.

The mission of the Center for Functional Genomics will be to elucidate key biological questions including “how the genome is regulated in each cell, tissue and organ in health and disease”, “what are the molecules and networks that drive biological activity in cells, tissues, organs”, and “how to modify genome regulation and genome output in health and diseases”. We will identify and characterize functional and regulatory non-coding genomic element networks in different cells and tissues of the human body, with the goal to identify the grammar of the genome, which will ultimately provide deeper understanding of genome function and enable biology and genomics medicine.

To address these challenges, the Centre develops original technologies to identify and functionally characterize regulatory elements, long non-coding RNA, genome conformation, interactomes of biological molecules in living cells and computational approaches to study genome regulation. These approaches will be broadly used to map the function and regulation of human genome in health and diseases across human diversity and ultimately derive actionable targets.

In this context, successful candidate(s) will engage in one or more of the following areas

  1. Development and applications of original technologies to comprehensively analyze function and regulation of genomes, transcriptomes, interactomes genome-RNA-proteins and the biology of lncRNAs including those derived from repeat elements;
  2. Development and application of new concepts in single cell technologies, including single cell multiomics to analyze expression, interactomes, gene regulation and imaging, from single cells to tissues and organs level;
  3. Development and application of computational approaches for biological interpretation of genomics and multiomics data, with particular focus on the areas of the Center of Genomics and other research centers at the Human Technopole;
  4. Development of databases and tools to broadly analyze, display, distribute, reuse the data produced by the Center and in collaboration with other centers inside and outside HT.

Key tasks and responsibilities

The Group Leader will:

  • Develop and supervise the establishment of a world-class research programme in genomics;
  • lead their own research group;
  • foster a diverse and nurturing research environment through leading and mentoring members of their teams;
  • build effective links and collaborations within other HT research investigators;
  • develop and foster links between HT and other national and international research organizations;
  • contribute to the preparation of Centre reports to be reviewed by an external expert board;
  • actively participate in initiatives that pursue improvement of all aspects of HT;
  • actively participate in the co-organization and implementation of activities that will promote the image of HT in the international genomics community, such as symposia and workshops;
  • contribute to the establishment of a collaborative and open scientific environment by actively participating in meetings and seminar series internal to HT. This will foster synergies between the groups and propagation of knowledge;
  • raise third-party funding;
  • participate and helping to designing HT Core Facilities.

Job requirements

The selected candidates will have an outstanding record in various areas of Genomics, preferably with a strong track in technology development; computational biology and related areas; and interest in the analysis of human systems and diseases. The Centre for Genomics will be implementing strategic internal collaboration schemes and will work closely with other HT Research Centres to achieve synergies and reach joint goals. The selected candidates will possess scientific vision, leadership skills and be competitive in acquiring extramural grants and collaborative attitude. Basic requirements for the position include a PhD in a relevant science subject, and a proven record of scientific research output in the field of genomics and related area. Excellent organisational skills and a fluent command of English are essential.

Application Instructions

Please apply online sending a CV, a motivation letter, a project description and providing contacts for 3 to 4 potential referees.

The project description should be a maximum of 8 pages long and include both a short description of current and future research in the group in the context of HT.

Questions concerning the role and any queries regarding the terms and conditions should be sent to the Head of the HT Centre of Genomics, at

Additional Information

HT offers a highly collaborative, international and diverse work environment. The working language is English. HT will foster top quality, interdisciplinary research by promoting a vibrant environment consisting of independent research groups attracting outstanding graduate students and postdoctoral fellows with access to cutting-edge Core Facilities.

HT is an inclusive, equal opportunity employer offering attractive conditions and benefits appropriate to a leading, internationally competitive research organization. Researchers coming to Italy for the first time, or returning after residing abroad, benefit from very attractive income tax benefits. HT seeks to promote a collegial and family-friendly atmosphere. The remuneration package comprises a competitive salary, a comprehensive pension scheme, medical and other social benefits, as well as financial support for relocation and installation.

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© EuroJobsites 2021

EuroJobsites is a registered company number: 4694396 VAT number: GB 880 9055 04

Registered address: EuroJobsites Ltd, Unit 8, Kingsmill Business Park, Kingston Upon Thames, London, KT1 3GZ, United Kingdom

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