Research Technicians

HT - Human Technopole

Research Technicians

HT - Human Technopole

Milan, Italy

Job description

APPLICATION CLOSING DATE: November 13th 2021

The Human Technopole Foundation is looking for three Research Technicians in the Neurogenomics Centre.

We are looking for highly-motivated technicians who will provide laboratory support for projects involving human tissue processing, human stem cell and organoids culture, and cutting-edge molecular biology and neuroscience technologies.

The roles will be responsible for technical work in the Neurogenomics Center and in the lab of Prof. Giuseppe Testa, focused on the high definition modelling of neurodevelopmental disorders through the integration of brain organoids and multi-omic technologies.

S(he) will have the following main responsibilities:

  • Conducting experiments in the area of stem cell neurobiology, combining cutting-edge methods from molecular biology, genome editing, biochemistry, cell biology and organoids, with a strong emphasis on advanced human cell culture pipelines, single cell and spatial genomics approaches and tissue processing for 3D imaging;
  • Optimizing and scaling up pipelines to perform cell culture experiments in high throughput;
  • Generating/importing and optimizing new tools and protocols;
  • Generating reliable data for publication in the projects to which s/he is assigned and record all data and results in specified forms (with Electronic Lab Notebook and Laboratory Information Management System);
  • Providing technical support and supervision to other laboratory members, including introduction and teaching of new laboratory techniques and support on the use of lab equipment to lab members, as well as members from other laboratories of the Center;
  • Liaising with the Centre’s Lab Manager and other staff to write risk assessments and ensure that they are regularly updated;
  • Maintaining cell lines generated and banked in the lab, and ensure that all tissue culture users work according to health and safety guidelines and regulations;
  • Participating in key aspects of general lab management and organization (e.g., managing inventories and stocks of samples, reagents, equipment, and materials), in coordination with HT core facilities and service units.

Job requirements

  • At least 5 years of proven experience as Lab Technician;
  • Track record in the following areas: Advanced cell culture (preferably with human pluripotent stem cell lines, organoids and primary neural cell cultures, including gene editing); Molecular Biology (DNA and RNA manipulation, cloning, sequencing, RT-PCR and library preparation for next-generation sequencing applications), Protein Biochemistry (immunoblotting and immunoprecipitation techniques), Tissue processing and Histology (including advanced embedding techniques such as tissue micro arrays, tissue clearing, dissociation and tissue processing for single cell and spatial genomics, automatized stainings);
  • Fluency in English - HT is an international research institute;
  • Ability to manage competing priorities in a fast-paced environment and to work independently;
  • Strong interpersonal skills demonstrated by the ability to lead and gain the assistance and cooperation of others in a team endeavor;
  • Ability to build trust through operating with transparency and creating an open and positive environment;
  • Ability to work in a multi-cultural, multi-ethnic.

For specific enquires concerning the role only, please contact Prof. Giuseppe Testa, Head of the Centre for Neurogenomics giuseppe@humantechnopole1.recruitee.com (this email address should not be used to send applications).

Please apply sending a CV and motivation letter in English.

Additional Information

HT offers a highly collaborative, international culture to foster top quality, interdisciplinary research by promoting a vibrant environment consisting of independent research groups with access to outstanding graduate students, postdoctoral fellows and core facilities.

HT is an inclusive employer that fosters diversity and engages systematically to ensure that equal employment opportunities are provided without regard to age, race, creed, religion, sex, disability, medical condition, sexual orientation, gender identity or expression, national or ethnic origin or any other legally recognized status entitled to protection under applicable laws. HT offers attractive conditions and benefits appropriate to a leading, internationally competitive, research organisation that promotes a collegial and open atmosphere.

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