Postdoctoral Position - Role of the Actin Cytoskeleton in Peripheral Nerve Degeneration

Postdoctoral Position - Role of the Actin Cytoskeleton in Peripheral Nerve Degeneration

University of Antwerp

Antwerp, Belgium

Job description

This project will take advantage of exciting preliminary data that needs to be validated and further investigated in available cellular CMT models, including pluripotent stem cells (iPSCs) derived from CMT patients and isogenic controls. The project will entail differentiation of iPSC into motor neurons and their general and actin-tailored characterization. Furthermore, specific pathomechanistic hypotheses will be explored, suggested by our preliminary studies. Next to the iPSC technology, this project will make use of biochemistry, cell and molecular biology, Multi-Electrode Array (MEA) electrophysiology, interactomics, and advanced microscopy techniques. You will be embedded in a team of scientists working on complementary topics and model systems, allowing for helpful discussions and fruitful collaborations. At the same time, you will be expected to work independently and drive your own research project. You will be given the opportunity to supervise and be a (co-)promotor of Master’s students and potentially also Ph.D. students.

Profile

Essential

  • Ph.D. degree in biochemistry, cellular-, molecular-, neurobiology, or related disciplines;
  • Experience with molecular and cell biology, biochemistry, microscopy, and mammalian cell culture;
  • Advanced knowledge and experience in (actin) cytoskeleton biology;
  • At least one accepted first-author publication in an international peer-reviewed journal;
  • Capability to independently plan, execute and troubleshoot your daily work, and propose relevant research directions;
  • Motivation, flexibility, and team spirit;
  • Excellent verbal and written English communication skills.

Desirable but not required

  • Prior experience with iPSC technology.
  • Prior experience with cellular electrophysiology.

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© EuroJobsites 2021

EuroJobsites is a registered company number: 4694396 VAT number: GB 880 9055 04

Registered address: EuroJobsites Ltd, Unit 8, Kingsmill Business Park, Kingston Upon Thames, London, KT1 3GZ, United Kingdom

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