Post-doctoral Position - Tissue Specificity and Molecular Crosstalk of Steroid Hormone Receptors

Post-doctoral Position - Tissue Specificity and Molecular Crosstalk of Steroid Hormone Receptors

IGBMC - Institute of Genetics and Molecular and Cellular Biology

Strasbourg, France

Aim of the project:

The project aims at understanding the molecular mechanisms underpinning the tissue specificity and the crosstalk between steroid hormone receptors through integrative analyses. Our team has recently developed projects based on genome-wide characterization of transcription factor cistromes and transcriptomes in various tissues of genetically modified mice, thereby providing the unique opportunity to decipher the in vivo mode of action of nuclear receptors. The fellow’s tasks will be to identify tissue-specific receptor partners and characterize the associated epigenetic marks using cutting-edge technics like Atac-seq, Hi-C and Rapid Immunoprecipitation Mass Spectrometry (RIME). Genome-wide data obtained in various tissues will be strengthened in in vitro models to delineate these complex molecular mechanisms.

Requirements:

Applicants should have a PhD in biological science, a strong background in molecular biology with a sound knowledge in transcriptional regulation and chromatin remodeling.

Your responsibilities will include:

  • Molecular biological assays on tissues of genetically modified mice (ChIP-seq, Atac-seq, imaging, …);
  • Establishment of new genome-wide technics using in vivo models;
  • Bioinformatics analyses.

Apply Now

Don't forget to mention EuroScienceJobs when applying.

Share this Job

© EuroJobsites 2021

EuroJobsites is a registered company number: 4694396 VAT number: GB 880 9055 04

Registered address: EuroJobsites Ltd, Unit 8, Kingsmill Business Park, Kingston Upon Thames, London, KT1 3GZ, United Kingdom

Newsletter | Recruit | Advertise | Privacy | Contact Us

© EuroJobsites 2021

EuroJobsites is a registered company number: 4694396 VAT number: GB 880 9055 04

Registered address: EuroJobsites Ltd, Unit 8, Kingsmill Business Park, Kingston Upon Thames, London, KT1 3GZ, United Kingdom

This website uses cookies to make your experience better. Continued use of this website means you accept our cookie policy.  Accept Cookies