Postdoc Position with Spin-off Track: Designing Enhancers for Gene Therapy

Postdoc Position with Spin-off Track: Designing Enhancers for Gene Therapy

VIB

Leuven, Belgium

Job description

The Laboratory of Computational Biology is seeking an enthusiastic postdoc to design cell-type specific enhancers, and to evaluate their activity using massively parallel enhancer-reporter assays, such as CHEQ-seq and STARR-seq. The assays will be performed in vitro, as well as in vivo in mouse tissues. The main activities will involve wet-lab work, including cloning, transfections/transductions, imaging, and sequencing. This will be performed in close collaboration and iteration with computational scientists, and with disease experts within the University of Leuven, the VIB, and the University Hospital. In parallel, the candidate will explore the possibilities of technology transfer, by interacting with companies, and evaluating the possibilities to create a spin-off company.

This project is funded by a Proof-of-Concept grant from the European Research Council (ERC).

Profile

Required

  • PhD in the life sciences such as molecular biology, bio-engineering, or related fields;
  • Strong expertise of molecular biology (e.g., cloning techniques like Gibson, Gateway, ...);
  • Interested in gene regulation;
  • A computational and systems biology mindset, fast learner & team player;
  • Ability to collaboratively lead a multidisciplinary project with international and national partners in academia, industry and the clinic;
  • Project management and effective communication skills;
  • Good mastery of English language;
  • Interested in gene therapy;
  • Interested in tech transfer, Intellectual Property, biotech industry.

Appreciated

  • Experience with cell culture;
  • Experience with mouse models (Felasa C);
  • Experience with viral vectors (lenti, AAV);
  • Experience with either brain disease, liver disease, or cancer;
  • Experience with enhancers, transcription factors, and gene regulatory networks;
  • Experience with bioinformatics (R, Python).

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EuroJobsites is a registered company number: 4694396 VAT number: GB 880 9055 04

Registered address: EuroJobsites Ltd, Unit 8, Kingsmill Business Park, Kingston Upon Thames, London, KT1 3GZ, United Kingdom

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